News

TCGA, ISB Researchers Identify Potential Drug Targets for Leading Form of Deadly Liver Cancer

June 19, 2017 Researchers in ISB’s Shmulevich Lab and their colleagues in The Cancer Genome Atlas Research Network performed the first large-scale, multi-platform analysis of hepatocellular carcinoma, the predominant form of liver cancer. Study was published on June 15, 2017, in the journal Cell.

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ISB Consilience: Museum of Awe

The Museum of Awe is all around us; you just have to find a door. Attendees of the 2017 Consilience event, including ISB’s Dr.

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ISB Q&A: David Gibbs, Research Scientist

You have to have fun. ISB founder Dr.

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William Poole, 2013 undergrad intern

Former Undergrad Intern Publishes Algorithm in PLOS Computational Biology

Posted March 1, 2017 In a study published in PLoS Computational Biology, researchers at Institute for Systems Biology (ISB) have developed a multiscale mutation clustering algorithm (M2C) that identifies variable length regions with high mutation density in cancer genes. The M2C algorithm was developed by William Poole (first author on the paper), who started as a summer intern in 2013 as part of ISB’s Center for Systems Biology internship program…

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Sanger Institute’s COSMIC database expands cancer cloud capabilities at the Institute for Systems Biology

The Wellcome Trust Sanger Institute released this news on Feb. 20, 2017.

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Comprehensive study of esophageal cancer reveals several molecular subtypes, provides new insight into increasingly prevalent disease

The Cancer Genome Atlas Research Network recommends clinical trials organizers and drug manufacturers focus on newly discovered molecular subtypes GRAND RAPIDS, Mich., Jan.

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ISB Gets $3.4M NIH Extension for Cancer Genomics Cloud

FOR IMMEDIATE RELEASE ISB Receives $3.4 Million Extension to NIH Contract to Continue Development of ‘Cancer Genomics Cloud’ with Google and CSRA SEATTLE, Oct.

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Vice President Biden Gives Cancer Moonshot Update

This week, Vice President Biden delivered an extensive update on the progress of the Cancer Moonshot initiative. ISB was mentioned in relation to the Cancer Genomics Cloud project.

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A Landscape of Pharmacogenomic Interactions in Cancer

The journal Cell published a study today (July 7) about the integrated analysis of drug response in 1,001 cancer cell lines. This study was undertaken by a large international group of researchers including ISB Senior Research Scientist Theo Knijnenburg.

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Not Just About Collecting Data

Genetic Engineering & Biotechnology News interviewed ISB’s Dr. Ilya Shmulevich for a feature article on systems biology.

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Systems Biology Digs Deep, Aims High

Dr. Ilya Shmulevich was recently interviewed for the following article in Genetic Engineering & Biotechnology News.

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New Publication in ‘Cancer Cell’

As part of The Cancer Genome Atlas project, the Shmuelvich Lab and colleagues published a paper in the journal Cancer Cell related to the rare cancer adrenocortical carcinoma. Read the summary: 3 Bullets: Adrenocortical carcinoma (ACC) is a rare, under-researched endocrine cancer with limited therapeutic options and overall poor outcome.

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Dr. Nyasha Chambwe, a postdoctoral fellow in the Shmulevich Lab at Institute for Systems Biology, discusses some data analysis with colleague Summer Elasady.

In the News: Basketball and Biology

Congratulations to Dr. Nyasha Chambwe on being featured in the May 20 issue of Puget Sound Business Journal’s “People in Research” column.

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New TCGA publication on adrenocortical carcinoma

Our group has contributed to a recent paper published by the TCGA Research Network on a study about adrenocortical carcinoma (ACC) in Cancer Cell. The study describes the comprehensive analysis of 91 ACC specimens from four continents using state of the art genomic technologies and computational methods.

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Bio-IT features Sheila Reynolds

Congrats to Sheila Reynolds on being featured on the Bio-IT World Conference site for her presentation on ISB’s Cancer Genomics Cloud project. Read the Q&A here.

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Ilya Shmulevich at GCPNext

Using Google Cloud Platform to Give Researchers Easier Access to Cancer Data

ISB’s Dr. Ilya Shmulevich attended Google Cloud Platform’s GCPNext conference in San Francisco and presented on ISB’s Cancer Genomics Cloud project.

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ISB Spotlight: Lisa Iype

Dr. Lisa Iype (Ilya Shmulevich group) has been promoted to Senior Bioinformatics Scientist.

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Event: Cancer Think Tank

Cure First is hosting the forum “Cancer Think Tank.” Speakers include ISB’s Dr.

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