New TCGA publication on adrenocortical carcinoma
Our group has contributed to a recent paper published by the TCGA Research Network on a study about adrenocortical carcinoma (ACC) in Cancer Cell. The study describes the comprehensive analysis of 91 ACC specimens from four continents using state of the art genomic technologies and computational methods. In addition to identification of novel ACC driver genes, pathways and refined subtypes, the AWG analysis revealed whole genome doubling (WGD) as a milestone in disease progression. We performed integrated analysis across different data types for this study and captured statistical associations in Regulome Explorer.